Laboratoire de Chimie Bactérienne UMR 7283

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10 novembre 2017: 1 événement


  • Séminaire IMM

    Vendredi 10 novembre 2017 11:30-13:00 - Enrique Flores - Sevilla Universidad, Spain

    Séminaire IMM

    Résumé : "Molecular basis of multicellularity communication in filamentous cyanobacteria"
    Some cyanobacteria grow as chains of cells that can be hundreds of cells long. Under nitrogen-limiting conditions, growth of some filamentous cyanobacteria requires the activity of two cell types : the vegetative cells that carry out oxygenic photosynthesis and the heterocysts that perform nitrogen fixation. The growth of heterocyst-forming cyanobacteria requires an intense activity of intercellular molecular exchange. Thus, (i) intercellular transfer of morphogens takes place to regulate heterocyst differentiation, and (ii) in the diazotrophic filament vegetative cells provide heterocysts with reduced carbon and heterocysts provide vegetative cells with fixed nitrogen. Recent research on heterocyst-forming cyanobacteria that will be discussed in this seminar has unravelled the presence of structures and mechanisms for intercellular molecular transfer that were previously unknown in bacteria and are analogous to the connexions of metazoan gap junctions.
    Recent references :
    Nieves-Morión M, Mullineaux CW & Flores E (2017) Molecular diffusion through cyanobacterial septal junctions. mBio 8:e01756-16.
    Herrero A, Stavans J & Flores E (2016) The multicellular nature of filamentous heterocyst-forming cyanobacteria. FEMS Microbiol. Rev. 40:831-854.
    Flores E, Herrero A, Forchhammer K & Maldener I (2016) Septal junctions in filamentous heterocyst-forming cyanobacteria. Trends Microbiol. 24:79-82
    Burnat M, Herrero A & Flores E (2014) Compartmentalized cyanophycin metabolism in the diazotrophic filaments of a heterocyst-forming cyanobacterium. Proc. Natl. Acad. Sci. USA 111(10):3823–3828.
    Flores E & Herrero A (2010) Compartmentalized function through cell differentiation in filamentous cyanobacteria. Nat. Rev. Microbiol. 8:39-50.
    Inv. : Christophe Bernard (LCB)

    Lieu : Salle Georges Morin

    En savoir plus : Séminaire IMM